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KMID : 0360220090500010034
Journal of the Korean Ophthalmological Society
2009 Volume.50 No. 1 p.34 ~ p.43
Early Results of Femtosecond Laser-Assisted Mushroom-Shaped Wound-Configurized Keratoplasty
Son Byeong-Jae

Kim Hong-Kyun
Abstract
Purpose: To report the results of femtosecond laser-assisted¡®mushroom-shaped wound-configurized keratoplasty¡¯in 6 patients based on the results of experimental models in rabbits¡¯and enucleated porcine eyes.

Methods: Mushroom-shaped donor corneal grafts were designed and transplanted in 3 rabbit eyes and 10 enucleated porcine eyes. The histologic findings were observed and wound burst pressure compared between penetrating keratoplasty (PKP) and mushroom-shaped keratoplasty. The¡®mushroom-shaped wound-configurized keratoplasty¡¯was subsequently performed in 6 eyes of 6 patients.

Results: In all eyes of the rabbits, histologic findings showed stable wound structure. In the porcine models, mushroom-shaped keratoplasty showed a better resistance to IOP than PKP after complete suture. Patients who underwent the surgery showed an improvement of over 2 lines in Snellen visual acuity after the operation. The mean follow-up period was approximately 11 months. Complete suture removal was performed within 6 months and accurate and stable wound structure was identified.

Conclusions: Wound-configurized keratoplasty with femtosecond laser and mechanical dissection¡¯has shown several advantages in the lamellar structure of the wound. Stable wound structure, less astigmatism, rapid suture removal and visual rehabilitation was achieved.
KEYWORD
Femtosecond laser, Mushroom-shaped keratoplasty
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